The UK will be "more outward-looking, global-facing" after the vote to leave the European Union, the Chancellor George Osborne has pledged.
Writing in the Wall Street Journal on Monday, Mr Osborne said there was an "overwhelming interest" for the US and UK to create even closer ties between the two countries.
Similarly to business secretary Sajid Javid, George Osborne is travelling the world in the coming months for preliminary talks over trade. Among the Chancellor's destinations are New York, China and Singapore.
Mr Osborne said: "While Britain's decision to leave the EU clearly presents economic challenges, we now have to do everything we can to make the UK the most attractive place in the world to do business.
"Britain and the US have been at the forefront of open trade in the last 200 years and pursuing a stronger relationship with our biggest trading partners is now a top priority.
"That's why I am travelling to the US, China and Singapore in the coming weeks and why my message to the world is that Britain may be leaving the EU, but we are not quitting the world."
He will meet finance bosses in New York before meeting US Treasury Secretary Jack Lew in London later this week.
In 2014, UK exports to the US reached £88 billion - equating to 17% of all UK exports.