By Marcus Leach
Lloyds Banking Group, managers of the Halifax and Bank of Scotland charity credit cards, are to withdraw them at the end of February.
The card scheme is no longer the most cost effective way of donating to charity, according to Lloyds.
In 2009 the cards raised around £1.1 million for Cancer Research UK, the NSPCC and the Scottish SPCA.
The charities say they are disappointed with the decision, but hope to explore other opportunities with the bank.
"Following a recent review, which noted the limited demand for charity cards in recent years, we have decided that we will no longer offer a charity credit card," a statement from the bank said.
"It was no longer proving to be a cost-effective method of donating to charity."